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  • Title: The net effect of ANCA on neutrophil extracellular trap formation.
    Author: Heeringa P, Rutgers A, Kallenberg CGM.
    Journal: Kidney Int; 2018 Jul; 94(1):14-16. PubMed ID: 29933842.
    Abstract:
    The formation of neutrophil extracellular traps induced by antineutrophil cytoplasmic autoantibodies has been implicated in the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis. Kraaij et al. now provide evidence that excessive neutrophil extracellular trap formation in vitro induced by sera from patients with antineutrophil cytoplasmic autoantibody-associated vasculitis is associated with active disease but is not dependent on the presence of antineutrophil cytoplasmic autoantibodies.
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