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  • Title: Localization of beta-adrenoceptors in the rabbit ear by light microscopic autoradiography.
    Author: Johnston HG, Summers RJ.
    Journal: Eur J Pharmacol; 1985 Sep 10; 115(1):97-101. PubMed ID: 2995086.
    Abstract:
    The beta-adrenoceptor antagonist [125I]cyanopindolol (CYP) was used to localize beta-adrenoceptors in sections of rabbit ear. Biochemical studies demonstrated that the binding was stereoselective, and that the beta-adrenoceptors are predominantly of the beta 2-subtype. Autoradiographic studies using 3H-Ultrofilm or nuclear emulsion coated coverslips showed high concentrations of beta 2-adrenoceptors present in the central ear artery, hyaline cartilage, nerve trunks, epithelium and sebaceous glands.
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