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  • Title: Examination of the Rotazyme II enzyme immunoassay for the diagnosis of rotavirus gastroenteritis.
    Author: Chernesky M, Castriciano S, Mahony J, DeLong D.
    Journal: J Clin Microbiol; 1985 Sep; 22(3):462-4. PubMed ID: 2995441.
    Abstract:
    Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron microscopy, the newer assay was found to be 99.4% sensitive and 97.3% specific for an overall agreement of 98.7%. After resolution of discordant results by blocking tests, the Rotazyme II enzyme immunoassay was shown to be more sensitive than electron microscopy and, therefore, 100% specific.
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