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Title: Malnutrition and cancer. Author: Randeria JD. Journal: J Environ Pathol Toxicol Oncol; 1985 Jul; 5(6):103-14. PubMed ID: 2995634. Abstract: In relation to cancer, malnutrition needs to be defined comprehensively as the carcinogenic effects produced by nutritional variables through multiple endogenous involvements. Nutritional factors act as primary effectors in four situations: carcinogens in food articles; affected bio-availability of nutrients; non-nutritive dietary items; harmful contaminants. The second situation resulting in malnutrition, often detected by metabolic pathology in high risk groups, is examined. Nutritional carcinogenesis is discussed in relevance to (1) ingestion of toxins; (2) dietary promoters; (3) type, relative proportions, interactions and bioavailability of micronutrients; (4) anti-carcinogenic or protective factors; and (5) the mixed-function oxidases. The etiological role of malnutrition preceding clinical cancer is firmly established. A host of unknown factors presently preclude but do not obliterate association of a specific type of malnutrition to a specific cancer type.[Abstract] [Full Text] [Related] [New Search]