These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Relationship between Vitamin D receptor gene polymorphism and renal cell carcinoma susceptibility.
    Author: Lin ZJ, Zhang XL, Yang ZS, She XY, Xie Y, Xie WJ.
    Journal: J Cancer Res Ther; 2018; 14(4):820-825. PubMed ID: 29970659.
    Abstract:
    AIM OF STUDY: Results on the association of Vitamin D receptor (VDR) gene polymorphism with renal cell carcinoma (RCC) susceptibility from the present reports are still debating. This meta-analysis was conducted to assess the association of VDR ApaI (rs7975232), BsmI (rs1544410), TaqI (rs731236), and Fok1 (rs2228570) gene polymorphisms with RCC risk. MATERIALS AND METHODS: The association studies were recruited from PubMed on May 1, 2016, and eligible reports were extracted and data were synthesized using meta-analysis method. RESULT: Six investigations were included into this meta-analysis for the relationship between VDR gene polymorphism and RCC susceptibility. In this meta-analysis, the ApaI A allele, AA genotype, aa genotype, and Fok1 FF genotype were associated with RCC susceptibility in Asians. However, VDR BsmI and TaqI gene polymorphisms were not associated with the RCC risk in Asians, Caucasians, and overall populations. Furthermore, Fok1 gene polymorphism was not associated with the RCC risk in Caucasians and overall populations. CONCLUSION: ApaI gene polymorphism and Fok1 FF genotype were associated with RCC susceptibility in Asians.
    [Abstract] [Full Text] [Related] [New Search]