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  • Title: Investigation of the parameters related to the formation of 99mTc-pyrophosphate complexes using gel chromatography column scanning.
    Author: Shafiq YF, Al-Janabi MA, Al-Azzawi HM, Abdel-Azeez MA, Al-Hissoni MH, Jassim MN.
    Journal: Nuklearmedizin; 1985 Jun; 24(3):146-9. PubMed ID: 2997754.
    Abstract:
    Using gel chromatography two different 99mTc-PPi complexes (complex I and II) were observed under various pH-values. In neutral medium complex II was the main product while in acidic or alkaline media complexes I and II were formed. Our results related to the organ distribution in mice revealed that complex II is a bone-seeking agent whereas complex I concentrates in the kidneys.
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