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  • Title: A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients.
    Author: Allan JS, Coligan JE, Lee TH, McLane MF, Kanki PJ, Groopman JE, Essex M.
    Journal: Science; 1985 Nov 15; 230(4727):810-3. PubMed ID: 2997921.
    Abstract:
    A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the acquired immune deficiency syndrome, was studied. This protein, which has a molecular weight of 27,000 (p27), was shown by amino acid sequencing to have a coding origin 3' to the env gene on the HTLV-III genome. The presence of antibodies to p27 in virus-exposed individuals indicated that this gene is functional in the natural host.
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