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  • Title: Large Porcine Model of Profound Acute Ischemic Cardiogenic Shock.
    Author: Møller-Helgestad OK, Ravn HB, Møller JE.
    Journal: Methods Mol Biol; 2018; 1816():343-352. PubMed ID: 29987833.
    Abstract:
    Cardiogenic shock is one of the leading causes of death following acute myocardial infarction affecting 10% of patients with large myocardial infarcts with a subsequent mortality rate of 50%. Here we describe a large porcine model of acute ischemic cardiogenic shock. Acute left or right ventricular failure can be achieved with close to a 100% success rate by stepwise injection of microspheres into the left or right coronary artery, respectively, and the method allows for titration of heart failure to a prespecified level.
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