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  • Title: Long-term shedding of Canine alphaherpesvirus 1 in naturally infected newborn pups.
    Author: Losurdo M, Dowgier G, Lucente MS, Cinone M, Camero M, Colaianni ML, Passantino G, Ventriglia G, Buonavoglia D, Decaro N.
    Journal: Res Vet Sci; 2018 Aug; 119():244-246. PubMed ID: 30005400.
    Abstract:
    The long-term shedding of Canine alphaherpesvirus 1 (CaHV-1) by neonatal pups with natural infection is reported. The pups belonged to a litter of 11 pointers of a breeding kennel in southern Italy, 9 of which developed a fatal form of systemic infection, as resulted by the detection of CaHV-1 in internal organs (kidney, liver, lung and brain) of one of this dogs and in the vaginal swab of their mother. The two remaining animals displayed a milder form of disease, with one pup showing ocular involvement, and underwent a progressive recovery. These pups were monitored from 11 to 36  days of age, showing a long-term shedding of the virus through the nasal and ocular secretions and the faeces. CaHV-1 shedding, as assessed by means of a specific and sensitive real-time PCR assay, occurred mainly through the nasal secretions, although the pup displaying ocular disease shed the virus at high titres and for a long period even in the ocular secretions.
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