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  • Title: A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis.
    Author: Liu X, Zhang W, Liu Y, Xu M.
    Journal: Case Rep Dermatol; 2018; 10(2):158-161. PubMed ID: 30022935.
    Abstract:
    Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multinucleated giant cells. The pathogenesis of the disease is unclear. We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period.
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