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  • Title: Effect of beta-funaltrexamine on retention of passive-avoidance conditioning.
    Author: Gallagher M.
    Journal: Behav Neural Biol; 1985 Nov; 44(3):499-502. PubMed ID: 3002317.
    Abstract:
    Rats received administration of an opiate antagonist immediately following single-trial passive-avoidance training. Retention of passive-avoidance conditioning was assessed 1 week after training. Compared to noninjected and vehicle-injected control groups, post-training naloxone (2.0 mg/kg) administration significantly increased retention. A comparable facilitation of retention was also observed when animals received post-training administration of beta-funaltrexamine (40 mg/kg). These data provide additional support for mu opiate receptor activity in the regulation of memory processes.
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