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  • Title: Enzymatic synthesis of mevalonate-5-(2-thiodiphosphate).
    Author: Jabalquinto AM, Cardemil E.
    Journal: Biochem Int; 1985 Nov; 11(5):653-60. PubMed ID: 3004492.
    Abstract:
    Mevalonate-5-(2-thiodiphosphate), a substrate analog for diphosphomevalonate decarboxylase, has been enzymatically prepared from mevalonate-5-phosphate and adenosine-5'-0-(3-thiotriphosphate) using phosphomevalonate kinase as a catalyst, in a 37% yield. The substrate properties of the synthesized compound are compared to those of the normal substrate of the enzyme.
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