These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ototoxic interactions of ethacrynic acid and streptomycin.
    Author: Mathog RH, Capps MJ.
    Journal: Ann Otol Rhinol Laryngol; 1977; 86(2 pt. 1):158-63. PubMed ID: 300585.
    Abstract:
    Various aminoglycoside antibiotics and potent diuretics are known to depress cochlear and vestibular function. Several clinical and research studies suggest that the drugs administered together produce enhanced ototoxicity. The present series of experiments determines the depressive effects of ethacrynic acid and streptomycin, alone or in combination, upon the vestibular system of the cat. The changes in function, when quantified, indicate an addition, rather than a potentiation of toxicity, and suggest different sites of action.
    [Abstract] [Full Text] [Related] [New Search]