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  • Title: Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter.
    Author: Noma Y, Sideras P, Naito T, Bergstedt-Lindquist S, Azuma C, Severinson E, Tanabe T, Kinashi T, Matsuda F, Yaoita Y.
    Journal: Nature; ; 319(6055):640-6. PubMed ID: 3005865.
    Abstract:
    Complementary DNA encoding the IgG1 induction factor, the first lymphokine directed to B lymphocytes, from a murine T-cell line has been cloned using a new strategy. The putative primary amino-acid sequence was deduced from the nucleotide sequence determined. The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells.
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