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  • Title: Distribution of 201Tl in the blood.
    Author: Nakamura K, Nishiguchi I, Takagi Y, Kubo A, Hashimoto S.
    Journal: Radioisotopes; 1985 Oct; 34(10):550-4. PubMed ID: 3006160.
    Abstract:
    Thallium-201 distribution in the blood was investigated both in vivo and in vitro. Thallium-201 was distributed into the erythrocytes and plasma with the ratio of 1.4 +/- 0.3 to 1.0, immediately after its administration. The uptake of 201Tl into the erythrocytes in vitro were affected by the incubation temperature and the presence of ouabain and KCl; indicating that the 201Tl was uptaken into cells partly through their membranes Na, K-ATPase. Erythrocytes could retain 201Tl in it, whereas 201Tl was present as free ion in the plasma. Thallium-201 was flew out of erythrocytes into the plasma, keeping the ratio of 201Tl in erythrocytes/plasma to be 1.9 +/- 0.2/1.0.
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