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  • Title: A cryptic transcription promoter in the myb oncogene of avian myeloblastosis virus.
    Author: Crochet J, Soret J, Perbal B.
    Journal: Virology; 1986 Apr 15; 150(1):252-9. PubMed ID: 3006338.
    Abstract:
    The potential regulatory signals contained in the v-myb oncogene of avian myeloblastosis virus have been inserted upstream to the herpes simplex type 1 thymidine kinase gene in order to test their promoter activity. The isolation of TK+ transformants after transfection of clone 1D(TK-) mouse cells with the resulting recombinant DNAs indicated that the expression of the TK gene was made possible by the myb-derived sequences. Analysis of the TK specific RNA expressed in different TK+ transformants revealed that the regulatory signals contained in v-myb correspond to a weak functional promoter.
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