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  • Title: Unusual presentation of erythema elevatum diutinum with underlying hepatitis B infection.
    Author: Hoy JV, Kikam A, Tyler K, Peters SB, Kaffenberger BH.
    Journal: Cutis; 2018 Jun; 101(6):462-465. PubMed ID: 30063775.
    Abstract:
    Erythema elevatum diutinum (EED) is a rare, chronic, cutaneous small vessel vasculitis of unclear pathogenesis. Classically, lesions present as symmetric red to purple plaques, papules, and nodules overlying joints. First-line therapy is dapsone. We present a case of EED with widespread lesions involving the hands, extensor arms and legs, and trunk. Multiple biopsies showed concentric intradermal perivascular inflammation with dermal fibrosis and leukocytoclastic vasculitis (LCV) suggesting EED in various stages of evolution. An extensive workup was positive for underlying hepatitis B infection. Our case represents the clinicopathologic spectrum that EED can present and emphasizes the importance of searching for an underlying etiology.
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