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  • Title: [Electron-microscopic study of monophasic spindle-cell synovial sarcomas].
    Author: Katenkamp D, Perevoshchikov AG, Raĭkhlin NT.
    Journal: Arkh Patol; 1985; 47(12):44-50. PubMed ID: 3006645.
    Abstract:
    Ultrastructural analysis of 9 monophasic spindle-cell synovial sarcomas revealed both undifferentiated tumour cells and histiocyte-like and fibroblast-like elements. Specialized contacts between tumour cells are found in 8 tumours, formation of the cavities of varying size (including vessel-like structure in 2 cases) in 7 tumours. Other findings included a discontinuous external lamina in 4 tumours; filopodium-like cell protrusions in 5, and spindle-shaped collagen bundles with long striation in 2 cases. The observation of cell contacts and cavities is of a diagnostic importance for monophasic synovial sarcoma. The differential diagnosis of these sarcomas and other spindle-cell tumours is discussed. Ultrastructural findings are interpreted as evidence of the monophasic spindle-cell synovial sarcoma origin from mesenchymal stem cells.
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