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  • Title: Relapsing Polychondritis: An Updated Review.
    Author: Borgia F, Giuffrida R, Guarneri F, Cannavò SP.
    Journal: Biomedicines; 2018 Aug 02; 6(3):. PubMed ID: 30072598.
    Abstract:
    Relapsing polychondritis is an immune-mediated systemic disease characterized by recurrent episodes of inflammation of cartilaginous and proteoglycan-rich tissues, resulting in progressive anatomical deformation and functional impairment of the involved structures. Auricular and nasal chondritis and/or polyarthritis represent the most common clinical features, but potentially all types of cartilage may be involved. Because of the pleomorphic nature of the disease, with non-specific symptoms at the onset, the diagnosis of relapsing polychondritis is often delayed. In this review article we provide a comprehensive look into clinical presentation, laboratory and instrumental investigations, diagnostic criteria, and therapeutic options.
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