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  • Title: Serum levels of vitamin D metabolites in children receiving total parenteral nutrition.
    Author: Kimura S, Nose O, Harada T, Maki I, Kanaya S, Tajiri H, Shimizu K, Yamaoka K, Seino Y, Yabuuchi H.
    Journal: JPEN J Parenter Enteral Nutr; 1986; 10(2):191-4. PubMed ID: 3007793.
    Abstract:
    Serum levels of 25-hydroxyvitamin D (25-OHD) and 1,25-dihydroxyvitamin D (1,25-(OH)2D) were measured on 19 occasions in seven children receiving total parenteral nutrition (TPN). The daily intakes of vitamin D3 ranged from 44 to 540 IU/day, and all serum samples were obtained after the same daily intake of vitamin D3 for more than 1 month. There was a significant positive correlation between serum 25-OHD levels and parenteral vitamin D3 intakes (r = 0.90, p less than 0.01). In this study, serum 25-OHD levels in all cases taking 200 to 360 IU/day of vitamin D3 were within the normal range. On the other hand, no significant correlation was found between serum 1,25-(OH)2D levels and vitamin D3 intakes, and serum 1,25-(OH)2D levels were normal or elevated in all cases.
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