These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: The effect of chronic physical exercise on the activity of hydrolytic enzymes in acute poisoning with parathion-methyl in rats.
    Author: Pawłowska D, Moniuszko-Jakoniuk J, Sołtys M.
    Journal: Pol J Pharmacol Pharm; 1985; 37(5):639-46. PubMed ID: 3008132.
    Abstract:
    Parathion-methyl, 10 mg/kg p.o., was given to unexercised rats, rats trained for 3 weeks and resting for 2 days, and trained rats subjected to a single physical exercise before treatment. The activity of cholinesterase (ChE) in the serum, of paraoxonase--in the serum and liver, and of beta-glucuronidase (beta-gluc)--in the serum, liver and intestine were determined 1 h after the treatment. Repeated physical exercise increased beta-gluc activity in the serum and liver and inhibited it in the intestine, while a single race after repeated exercise inhibited paraoxonase activity in the serum. Parathion-methyl inhibited ChE and paraoxonase activities and an increased beta-gluc activity in the serum. Repeated physical exercise and a single race, applied 2 days after the end of training, affects the activity of parathion-methyl in a significant yet diversified manner, dependent upon the examined biochemical parameters.
    [Abstract] [Full Text] [Related] [New Search]