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  • Title: Vincristine neurotoxicity enhanced in combination chemotherapy including both teniposide and vincristine.
    Author: Griffiths JD, Stark RJ, Ding JC, Cooper IA.
    Journal: Cancer Treat Rep; 1986 Apr; 70(4):519-21. PubMed ID: 3009012.
    Abstract:
    A high incidence of severe peripheral neuropathy occurred during the pilot study of a new regimen for the treatment of non-Hodgkin's lymphoma. The clinically observed incidence and severity of vincristine-induced peripheral neuropathy was considerably enhanced by the sequential use of vincristine and teniposide in this combination chemotherapy.
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