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  • Title: Studies on herpes simplex virus type 1 glycoproteins using monoclonal antibodies.
    Author: Koga J, Chatterjee S, Whitley RJ.
    Journal: Virology; 1986 Jun; 151(2):385-9. PubMed ID: 3010559.
    Abstract:
    Monoclonal antibodies against herpes simplex virus type 1 glycoproteins were isolated and utilized to study the synthesis and processing of glycoproteins B, C, and D (gB, gC, gD, respectively). Monoclonal antibodies against both gB and gD had higher virus-neutralizing activity when compared to that of gC. Differences among these glycoproteins were observed in their time of appearance in the virus-infected cells. The presence of gD was detected at a very early stage of infection when compared to gB and gC. The localization of these glycoproteins during their synthesis and processing was studied.
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