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  • Title: Immunological findings in immunoblastic lymphadenopathy. A detailed case study.
    Author: Kreisler JM, Moreno E, Moneo I, Bootello A, Bouza E, De Letona JM, Anaya A.
    Journal: Clin Exp Immunol; 1977 Mar; 27(3):497-501. PubMed ID: 301074.
    Abstract:
    Several immunological parameters were investigated in a patient with immunoblastic lymphadenopathy (IBL). An increased concentration of polyclonal immunoglobulins, the presence of autoantibodies in the serum and an increased level of B lymphocytes with an abnormal DNA synthesis response to LPS in peripheral blood were the most salient features. The findings suggest that in IBL there is a numerical as well as a functional alteration of peripheral blood lymphocytes. We propose that the alteration was due to either an escape of lymphocytes from central lymphatic organs or a defect in maturation of peripheral blood lymphocytes.
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