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  • Title: Pseudocholinesterase activity and atracurium v. suxamethonium block.
    Author: Baraka A, Wakid N, Noueihed R, Karam H, Bolotova N.
    Journal: Br J Anaesth; 1986; 58 Suppl 1():91S-95S. PubMed ID: 3011044.
    Abstract:
    Serum pseudocholinesterase activity in pregnant women was assayed spectrophotometrically using either propionylthiocholine or suxamethonium as substrate. All patients had a normal phenotype as indicated by normal dibucaine and fluoride numbers. However, the mean cholinesterase activity was lower than in the general population. There was a negative correlation between cholinesterase activity and the duration of neuromuscular blockade following suxamethonium, but no correlation was observed between the cholinesterase activity and the duration of block following atracurium.
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