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  • Title: Diagnostic value of urinary cyclic AMP measurement in patients with calcium nephrolithiasis.
    Author: Bianchi G, Galvanini G, Schiavone D, Facchinetti R, Malossini G, Lo Cascio V, Mobilio G.
    Journal: Int Urol Nephrol; 1985; 17(4):311-4. PubMed ID: 3011700.
    Abstract:
    One hundred patients with recurrent calcium nephrolithiasis were submitted to the Pak test. At fasting state hypercalciuria was found in 27 cases, while a group of 16 further patients became hypercalciuric after oral calcium load. Only measurement of urinary cAMP excretion in both conditions made it possible to diagnose renal hypercalciuria in 9 out of 27 patients in the former group; according to test results 4 patients were expected to have primary hyperparathyroidism, but afterwards the disease was identified in only one case.
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