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  • Title: [Radiotherapy of carcinoma of the paranasal sinuses].
    Author: Schlappack OK, Dobrowsky W, Schratter M, Grasl M, Schmid AP, Swoboda H, Mailath G, Pavelka R, Braun O.
    Journal: Strahlenther Onkol; 1986 May; 162(5):291-9. PubMed ID: 3012810.
    Abstract:
    Carcinomas of the paranasal sinuses are usually advanced when diagnosed and present a therapeutic challenge. During the period between February 1970 and June 1981 44 patients were treated. 22 received postoperative irradiation, seven in combination with chemotherapy. 18 patients were treated with radiation alone, eleven with concomitant chemotherapy. Four patients received preoperative irradiation, three in combination with chemotherapy. The three-year survival is 43% and the five-year survival 33%. For those 26 patients who were irradiated pre- or postoperatively with or without concomitant chemotherapy the five-year survival is 45%. We believe the patient will be afforded the greatest opportunity for cure with the combined efforts of the radiotherapist and the surgeon. The combination of chemotherapy and radiotherapy did not provide better results but increased acute and chronic toxicity of the therapy.
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