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  • Title: Favorable Renal Outcome of Japanese Children with Severe IgA Nephropathy With Nephrotic Syndrome.
    Author: Fujinaga S, Nishino T.
    Journal: Indian Pediatr; 2018 Jul 15; 55(7):605-607. PubMed ID: 30129546.
    Abstract:
    BACKGROUND: Nephrotic syndrome is a rare but severe feature of IgA nephropathy. CASE CHARACTERISTICS: Nine Japanese children with severe IgA nephropathy with nephrotic syndrome. INTERVENTION: All received low-dose intravenous methylprednisolone (IVMP) within five weeks after the disease onset. Eight out of nine patients achieved resolution of proteinuria without severe adverse events. MESSAGE: Early low-dose intravenous methylprednisolone may be safe and effective for children with severe IgA nephropathy with nephrotic syndrome.
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