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  • Title: The effect of the introduction of the three-vessel view on the detection rate of transposition of the great arteries and tetralogy of Fallot.
    Author: Everwijn SMP, van Nisselrooij AEL, Rozendaal L, Clur SB, Pajkrt E, Hruda J, Linskens IH, van Lith JM, Blom NA, Haak MC.
    Journal: Prenat Diagn; 2018 Nov; 38(12):951-957. PubMed ID: 30132937.
    Abstract:
    OBJECTIVES: The aim of this study was to analyze the annual detection rate (DR) of transposition of the great arteries (TGA) and tetrology of Fallot (ToF), after the introduction of the three-vessel view as a mandatory plane in 2012. METHODS: All registered TGA and ToF cases were retrospectively extracted from our registry between 2007 and 2016. We compared the DR in a 10-year period, before 2011, with the DR of TGA and ToF after 2012. RESULTS: In the period before 2012, 23 of the 52 TGA cases were prenatally detected (44.2%), compared with 42 of the 51 cases (82.4%) after 2012. For ToF, the DRs increased from 28 of 64 cases (43.8%) to 42 of 62 cases (67.7%) in the aforementioned periods. The increase in DRs for both defects was statistically significant (P ≤ 0.001 and P ≤ 0.05). CONCLUSIONS: In this nationally organized prenatal screening program with a quality monitoring system and a uniform protocol, DRs of 82.4% for TGA and 67.7% for ToF were reached after the introduction of the three-vessel view as a mandatory item. The three-vessel view significantly contributes to the detection of these conotruncal anomalies.
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