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  • Title: A filamentous distribution for the herpes simplex virus type 2-encoded major DNA-binding protein.
    Author: Rose DS, Shriver K, Latchman DS, LaThangue NB.
    Journal: J Gen Virol; 1986 Jul; 67 ( Pt 7)():1315-25. PubMed ID: 3014046.
    Abstract:
    Monoclonal antibodies reacting with the herpes simplex virus (HSV)-encoded major DNA-binding protein defined an intracellular filamentous network. This network was associated predominantly with the infected cell nucleus and occurred in cells infected with HSV type 2. It did not co-distribute with microfilaments, microtubules or intermediate filaments, and DNA synthesis was required for its formation. We suggest explanations for the occurrence and function of this novel filamentous network structure.
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