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  • Title: Effect of cupric ions on the permeability of erythrocyte membrane to non-electrolyte spin labels.
    Author: Gwozdzinski K.
    Journal: Physiol Chem Phys Med NMR; 1985; 17(4):431-4. PubMed ID: 3014577.
    Abstract:
    The addition of cupric ions caused decreased permeability to hydrophilic molecules and increased permeability to hydrophobic molecules. These results suggest that TEMPOL penetrates the erythrocyte in a different way than TEMPO. Penetration of TEMPOL is controlled by-SH groups, while TEMPO probably diffuses through the lipid bilayer. Cupric ions increase the permeability of erythrocyte membranes to both non-electrolytes in vivo.
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