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  • Title: [Etiological factors for calculus-associated seminal vesiculitis: Analysis of calculus composition in 6 cases].
    Author: Liu GL, Wang GY, Wu KR, Yin WQ, Wu WJ.
    Journal: Zhonghua Nan Ke Xue; 2018 Feb; 24(2):128-132. PubMed ID: 30156071.
    Abstract:
    OBJECTIVE: To explore the etiological factors for calculus-associated seminal vesiculitis by analyzing the composition of seminal vesicle calculus samples. METHODS: This retrospective study included 6 cases of recurrent hematospermia diagnosed with seminal vesicle calculus by non-contrast pelvic CT. The patients were aged 28 to 69 years, with persistent or recurrent hematospermia for 3 months to 6 years, and 5 of them with a history of acute urethritis. All the patients underwent seminal vesiculoscopy, which confirmed calculus-associated seminal vesiculitis. The calculus samples were obtained with a spiral dislodge and their composition was determined with a second-generation infrared calculus composition analyzer. The patients were followed up for 2 to 12 weeks postoperatively, during which non-contrast pelvic CT was employed for observation of recurrent calculus in the reproductive tract. RESULTS: Pelvic CT scanning indicated recurrence of seminal vesicle calculus in 3 cases at 12 weeks postoperatively, of which, 2 were accompanied with recurrent hematospermia, both observed at 4 weeks after operation. As for the composition of the calculus, the infrared calculus composition analyzer revealed struvite (magnesium ammonium phosphate hexahydrate) in 5 cases and a mixture of calcium oxalate dihydrate, calcium oxalate monohydrate, and carbonate apatite in the other one. CONCLUSIONS: Seminal vesicle calculi are most commonly composed of struvite, and infection is the main etiological factor for calculus-associated seminal vesiculitis. 目的: 通过对精囊结石标本进行成分分析，初步探讨精囊结石患者的致病因素。方法: 回顾性分析6例反复血精且盆腔CT平扫提示精囊结石患者的临床资料。患者年龄28~69岁，持续或反复血精3个月至6年。6例中5例有急性尿道炎史。所有患者均接受精囊镜检查治疗术，术中证实精囊炎合并精囊结石，并以套石篮套取结石标本。利用第二代红外光谱结石成分分析仪分析6例精囊结石成分。随访患者2周至3个月，复查盆腔CT平扫观察有无生殖道结石复发。结果： CT平扫结果提示术后3个月有3例患者精囊结石复发，其中2例血精复发，其复发时间均在手术后1个月。6例精囊结石中有5例含有感染性结石成分——六水磷酸镁铵，仅有1例结石成分为二水草酸钙、一水草酸钙以及碳酸磷灰石的混合性结石。结论： 6例精囊结石以六水磷酸镁铵结石最常见，推测精囊结石合并精囊炎可能的致病因素主要为感染。.
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