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  • Title: Acute regrowth and dissemination of a mature spinal cord teratoma after partial resection.
    Author: Kawai M, Nagoshi N, Iwanami A, Mikami S, Tsuji O, Fujita N, Yagi M, Watanabe K, Ishii K, Nakamura M, Matsumoto M.
    Journal: BMJ Case Rep; 2018 Sep 01; 2018():. PubMed ID: 30173127.
    Abstract:
    A 23-year-old man presented with difficulty walking and leg pain and numbness. MRI revealed a cystic mass at Th11-12 and a pineal-region tumour. The patient underwent surgery to resect the thoracic-level mass. The tumour adhered strongly to the neural tissue and could only be partially resected. On pathological examination, the resected tumour was diagnosed as a mature teratoma. The tumour regrew and disseminated within 3 months after resection. Both the spinal cord tumour and the tumour in the pineal region shrank significantly after chemotherapy and radiotherapy. Although the tumour was pathologically diagnosed as a mature teratoma, we suspect that the residual tumour contained an immature or malignant component. Thus, careful follow-up observation is mandatory after partial resection of a mature teratoma. In addition, because teratomas can disseminate in the central nervous system, the presence of teratoma should prompt an examination of both the spinal cord and brain.
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