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  • Title: Is sonoelastography a helpful method of evaluation to diagnose Sjögren's syndrome?
    Author: Pia LJ, Juan BM, Frank P, Angela AA, Jose G, Juan de Dios BS.
    Journal: Int J Rheum Dis; 2019 Feb; 22(2):175-181. PubMed ID: 30187679.
    Abstract:
    OBJECTIVE: A new sonoelastography technique - virtual touch tissue quantification of acoustic radiation force impulses (ARFI) - offers a promising method for measuring tissue rigidity. The aim of this study was to assess the usefulness of ARFI for diagnosing Sjögren's syndrome (SS). METHODS: This transversal prospective study included 41 patients with SS according to American-European Consensus Group (AECG) criteria, and a control group without symptoms. All subjects underwent ARFI high-resolution ultrasound assessment of the parotid glands (PG) and submandibular glands (SMG). RESULTS: In patients with SS, parotid gland shear wave velocity (SWV) was 2.08 m/s ± 0.55, significantly higher than in control subjects (1.2 m/s ± 0.17) (P = 0.0001); submandibular gland SWV was higher in SS patients (2.12 m/s ± 0.44) than control subjects (1.56 m/s ± 0.16) (P = 0.001). CONCLUSIONS: Acoustic radiation force impulses sonoelastography can assist diagnosis of SS, and is a non-invasive and fast method of detecting pathological changes to the parotid and submandibular glands.
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