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  • Title: The association between urinary tract infection during pregnancy and preeclampsia: A meta-analysis.
    Author: Yan L, Jin Y, Hang H, Yan B.
    Journal: Medicine (Baltimore); 2018 Sep; 97(36):e12192. PubMed ID: 30200124.
    Abstract:
    OBJECTIVE: The association between urinary tract infection (UTI) during pregnancy and preeclampsia (PE) continues to be the subject of debate. This meta-analysis aimed to examine the relationship between UTI during pregnancy and PE. STUDY DESIGN: Observational studies up to October 2017, extracted from Medline, PubMed, Cochrane Library, and Embase databases, were included in the analysis. Data were extracted to 4-fold table, and the pooled odds ratio (OR) and 95% confidence intervals (CIs) of respective studies were calculated. Then meta-analysis was performed. RESULTS: Nineteen studies qualified the inclusion criteria. Urinary tract infection during pregnancy was found to be a risk factor for the development of PE (OR: 1.31, 95% CI: 1.22-1.40). CONCLUSION: Occurrence of UTI during pregnancy increases the risk of PE in pregnant women. Screening for, and treatment of UTI should be part of routine antenatal care, especially in developing countries.
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