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  • Title: [Electron microscopy of Aujeszky's disease virus in explants of Gasser's ganglion from pigs with a latent infection].
    Author: Valícek L, Smíd B, Rodák L, Jurák E.
    Journal: Vet Med (Praha); 1986 Aug; 31(8):469-76. PubMed ID: 3020761.
    Abstract:
    Different developmental stages of the Aujeszky's disease virus were demonstrated by electron microscopy in the ultra-thin slices by the cultivated fragments of the Gasserian ganglion (G. g.) of two pigs latently infected with the Aujeszky's disease virus (ADV). In a pig vaccinated with the inactivated vaccine against the disease, the virus was detected in the G. g. cells 186 days after virus challenge, the reactivation of latency being obtained after immunosuppression with dexamethasone. In the non-vaccinated pig the virus was detected in G. g. cells after three months from experimental infection. In the ultra-thin slices the largest amount of virus was located in the nuclei and cytoplasm of satellite and Schwann's cells, in the connective-tissue cells and in the extracellular space. In the ganglion cells the virus was present in the cytoplasm and sporadically in the myelinized axons.
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