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  • Title: Comparison of serological tests for detection of antibodies to Sendai virus in rats.
    Author: Rottinghaus AA, Gibson SV, Wagner JE.
    Journal: Lab Anim Sci; 1986 Oct; 36(5):496-8. PubMed ID: 3022063.
    Abstract:
    The sensitivities of the enzyme-linked immunosorbent assay, complement fixation and hemagglutination inhibition tests for detection of serum antibodies to Sendai virus were compared. Virus antibody-free, 4-week-old, female Fischer 344 rats were inoculated intranasally with either egg-propagated Sendai virus or a noninfectious egg control preparation. None of the rats became ill clinically or developed pulmonary lesions characteristic of Sendai virus infection. The enzyme-linked immunosorbent assay was the most sensitive of the three tests, particularly in detection of early antibodies to Sendai virus and detection of small amounts of antibody.
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