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Title: Magnetic fields differentially inhibit mu, delta, kappa and sigma opiate-induced analgesia in mice. Author: Kavaliers M, Ossenkopp KP. Journal: Peptides; 1986; 7(3):449-53. PubMed ID: 3022253. Abstract: An exposure for 60 min to a 0.5 Hz rotating magnetic field (1.5-90 G) significantly attenuated the daytime analgesic effects of the mu and kappa opiate agonists, morphine and U50,488H, respectively, and significantly inhibited the analgesic actions of the delta agonist, D-Ala2-D-Leu5-enkephalin, in mice. The magnetic stimuli had no significant effects on the analgesic effects of the prototypic sigma opiate agonist (+/-) SKF-10,047. These results show that exposure to relatively weak magnetic stimuli has significant and differential inhibitory influences on various opioid systems.[Abstract] [Full Text] [Related] [New Search]