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  • Title: Isolation and sequencing of a cDNA clone homologous to the v-sis oncogene from human endothelial cells.
    Author: Tong BD, Levine SE, Jaye M, Ricca G, Drohan W, Maciag T, Deuel TF.
    Journal: Mol Cell Biol; 1986 Aug; 6(8):3018-22. PubMed ID: 3023958.
    Abstract:
    A clone containing the 3' end of the mRNA for the human c-sis gene (homologous to the B chain of platelet-derived growth factor) was isolated from a cDNA library derived from human umbilical vein endothelial cells and then sequenced. The analysis of possible translation products in all three reading frames indicated that the A chain of platelet-derived growth factor was not coded for within the 3' end of the c-sis mRNA. The 3' end of the mRNA for c-sis is contained in or adjacent to exon 6.
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