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  • Title: Rifampin Resistance in Staphylococci after Rifaximin Intake for Surgical Prophylaxis in Elective Colorectal Surgery.
    Author: Padilla E, Oms L, Espejo E, Gómez L, Pagespetit L, Boada N, Bella F, Pérez J.
    Journal: Antimicrob Agents Chemother; 2018 Dec; 62(12):. PubMed ID: 30249689.
    Abstract:
    The aim of our study was to determine whether rifampin resistance emerges in human skin staphylococci after oral intake of rifaximin for surgical prophylaxis. Rifampin-resistant staphylococci appeared on the skin of 32 out of 74 patients (43.2%) two weeks after prophylactic treatment with rifaximin. In all cases, the resistant strains were coagulase-negative staphylococci. The resistance completely reverted after three months. This study shows the emergence of transient resistance to rifampin after rifaximin intake.
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