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  • Title: Tricholumin A, a Highly Transformed Ergosterol Derivative from the Alga-Endophytic Fungus Trichoderma asperellum.
    Author: Song YP, Shi ZZ, Miao FP, Fang ST, Yin XL, Ji NY.
    Journal: Org Lett; 2018 Oct 05; 20(19):6306-6309. PubMed ID: 30256119.
    Abstract:
    Tricholumin A (1) with an unprecedented carbon skeleton was isolated from the fungus Trichoderma asperellum cf44-2, an endophyte from the marine brown alga Sargassum sp. Its structure and relative configuration were identified by extensive 1D/2D NMR and mass spectrometric data, and the absolute configuration was assigned by X-ray diffraction and ECD calculations. Compound 1 represents a highly transformed ergosterol derivative, and it exhibited inhibition of some pathogenic microbes and marine phytoplankton species.
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