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  • Title: Urolithiasis in a patient ingesting pure silica: a scanning electron microscopy study.
    Author: Leusmann DB, Pohl J, Kleinhans G.
    Journal: Scan Electron Microsc; 1986; (Pt 2):757-60. PubMed ID: 3026031.
    Abstract:
    A patient who repeatedly produced urinary calculi, had consumed about 3 g of cristobalite (SiO2) per day for many years. Investigations using scanning electron microscopy revealed minute particles containing silicon in the core of the stone as well as in urine sediment. A mechanism similar to that proposed for the effect of silicon-containing drugs against gastric ulcer, may play a role in this formation of silicon-containing urinary stones.
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