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  • Title: Genetic studies of low abundance human plasma proteins. III. Polymorphism of the C1R subcomponent of the first complement component.
    Author: Kamboh MI, Ferrell RE.
    Journal: Am J Hum Genet; 1986 Dec; 39(6):826-31. PubMed ID: 3026176.
    Abstract:
    Genetic polymorphism of the C1R subcomponent of human complement component C1 has been detected in normal plasma samples using the high resolving power of isoelectric focusing in 6 M urea followed by immunoblotting. There are two common alleles at the C1R structural locus that show autosomal codominant inheritance. The C1R*1 and C1R*2 allele frequencies in U.S. white and U.S. black blood donors are: .934, .066, and .899, .101, respectively.
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