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Pubmed for Handhelds

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  • Title: Use of double spin-labeled histones to monitor histone-chromatin integration.
    Author: Barber MJ, Trudeau W, Byvoet P.
    Journal: Biochem Biophys Res Commun; 1986 Dec 15; 141(2):434-9. PubMed ID: 3026383.
    Abstract:
    Tyrosine-specific nitroxide spin labels have been synthesized that utilize either deuterium or deuterium and [15N] isotopic substitution within the nitroxide ring. These probes have been used to differentially spin label and simultaneously monitor both histones H1 and H5, during the displacement of endogenous spin-labeled H1 from reconstituted chromatin by exogenously added spin-labeled H5.
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