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  • Title: Upper aerodigestive tract frostbite from inhalation of automotive nitrous oxide.
    Author: Chan SA, Alfonso KP, Comer BT.
    Journal: Ear Nose Throat J; 2018 Sep; 97(9):E13-E14. PubMed ID: 30273435.
    Abstract:
    Nitrous oxide, a cryogenic gas, may be abused as an inhalant for its euphoric properties. If inhaled, nitrous oxide may cause frostbite to the oral cavity and upper aerodigestive tract, with possible airway compromise due to edema. In this article we describe what is, to the best of our knowledge, the first case of intentional inhalation of nitrous oxide from an automotive nitrous oxide canister and discuss the management and mechanism of the patient's injury.
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