These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A [11 C] CO dispensing system for rapid screening of carbonylation reactions.
    Author: Van der Wildt B, Shen B, Chin FT.
    Journal: J Labelled Comp Radiopharm; 2018 Dec; 61(14):1110-1114. PubMed ID: 30286517.
    Abstract:
    [11 C] CO is a highly versatile synthon that allows for labeling at carbonyl positions of many molecules by means of transition metal-mediated carbonylation reactions. The intrinsic complexity of carbonylation reactions often requires tedious screening of reaction conditions for obtaining satisfying yields. Herein, a [11 C] CO dispending system for performing multiple reactions with a single batch of cyclotron-produced [11 C]CO2 is described. This semiautomated setup allows for more rapid and efficient screening of reactions and reaction conditions compared with the traditional "one beam for one reaction" strategy.
    [Abstract] [Full Text] [Related] [New Search]