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  • Title: Experience with 24-h infusions of ifosfamide/mesna in small cell lung cancer.
    Author: Cantwell BM, Harris AL, Bozzino JM.
    Journal: Cancer Chemother Pharmacol; 1986; 18 Suppl 2():S29. PubMed ID: 3028660.
    Abstract:
    Two studies were carried out (A and B) in order to assess the effectiveness of ifosfamide administered with mesna (IFO/M) in the treatment of small cell lung cancer. The first study (A) was a cross-over study; the second (B) was a randomized trial, and in B IFO/M was evaluated earlier in the course of the disease. IFO/M given be infusion is effective as second-line therapy and can be administered with other cytotoxics at the doses reported here earlier in the course of the disease. The complete remission rates were high.
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