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  • Title: [Effect of ACTH fragments on the aggressive-defensive behavior of the rat].
    Author: Sever'ianova LA, Plotnikov DV.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1986 Dec; 72(12):1614-8. PubMed ID: 3028874.
    Abstract:
    ACTH4-10 and ACTH5-10 enhanced the fear response and footshock-induced aggression in male rats (50 and 150 mcg/kg, i.p.). ACTH4-10 seemed to produce the corticotropin (ACTH1-39) neuromodulatory behavioral effect which involved the facilitation of the brain muscarinic receptor activation.
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