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  • Title: Response of supraoptic magnocellular neurons to stimulation of forebrain alpha-adrenoceptors.
    Author: Mitchell LD, Callahan MF, Wilkin LD, Johnson AK.
    Journal: Brain Res; 1986 Dec 10; 399(2):346-51. PubMed ID: 3030490.
    Abstract:
    Effects of alpha-adrenoceptor agents on electrophysiologically and immunohistochemically identified supraoptic nucleus (SON) vasopressin (VP) units were investigated by intracarotid infusion. Clonidine, an alpha 2-adrenoceptor agonist always excited SON units and alpha 2-adrenoceptor antagonists consistently inhibited them. alpha 1-Adrenoceptor agents produced inconsistent responses. The results implicate forebrain alpha 2-adrenergic receptors in the excitation of SON VP neurons.
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