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  • Title: Chemical and biological properties of 2,6-diisopropyl IDA labelled with 99mTc.
    Author: Zmbova B, Djokić D, Ninković D, Obradović V, Kostić K.
    Journal: Int J Rad Appl Instrum A; 1987; 38(1):35-40. PubMed ID: 3030967.
    Abstract:
    A procedure is described for the synthesis of 2,6-diisopropyl IDA (DISIDA) and for preparation of the radiopharmaceutical by "instant technique". The chemical parameters affecting the formation of the Sn(II)-DISIDA complex were also determined. Biological studies involved lyophylic measurements, determination of binding constants as well as rate of binding to proteins and biodistribution. Clinical investigation demonstrated good hepatobiliary features of this radiopharmaceutical.
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